{
 "schema_version": 1,
 "generated": "2026-10-31",
 "id": "google-deepmind-alphafold3--choose-an-alphafold-3-weights-variant",
 "repo": "google-deepmind/alphafold3",
 "repo_url": "https://github.com/google-deepmind/alphafold3",
 "repo_slug": "google-deepmind-alphafold3",
 "title": "Pick the right AlphaFold 3 weights for your project",
 "page_title": "How to pick the right AlphaFold 3 weights for your project with Alphafold3",
 "summary": "Compare the standard weights with the SynthID Bio-structure and Leaving Atom variants before you run.",
 "who": "A team deciding how to run AlphaFold 3 for commercial or watermarked work.",
 "problem": "Picking the wrong weights or the wrong route can break the terms you agreed to.",
 "outcome": "A clear decision on which weights and which route fit your use.",
 "steps": [
  "Read the Obtaining Model Parameters section and the linked WEIGHTS_TERMS_OF_USE.md",
  "Note the SynthID Bio-structure version, which predicts watermarked structures, and the AF3 Leaving Atom variant fine-tuned for leaving atom handling",
  "For non-commercial one-off work consider alphafoldserver.com, which the README says has a more limited set of ligands and covalent modifications",
  "For commercial use follow the README pointer to Gemini Enterprise Agent Platform on Google Cloud"
 ],
 "agent_prompt": "Using google-deepmind/alphafold3, compare the standard, SynthID Bio-structure and Leaving Atom weights plus the server and Google Cloud routes for <my project>, and tell me which fits.",
 "agents": [
  "claude-code",
  "codex",
  "cursor",
  "gemini-cli"
 ],
 "difficulty": "Beginner",
 "time": "30 minutes",
 "basis": "readme",
 "caveat": "This is a reading and decision task; it does not run a prediction.",
 "category": "Security and science",
 "tags": [
  "Security and science"
 ],
 "lang": "",
 "requirements": [
  "The model parameters, which you may only use if received directly from Google, under the weights terms of use",
  "Docker and an NVIDIA GPU for the inference step",
  "The genetic and template databases for the data pipeline, mounted into the container",
  "A fold_input.json describing your sequences, model seeds, dialect and version"
 ],
 "risk": "none",
 "seen_in_the_wild": false,
 "mentioned_publicly": false,
 "risks": [
  {
   "tag": "credentials",
   "notice": "All weight variants are subject to the AlphaFold 3 weights terms of use."
  }
 ],
 "best": false,
 "score": 0.8,
 "evidence": [],
 "url": "https://dedupedai.com/use-cases/google-deepmind-alphafold3/choose-an-alphafold-3-weights-variant/",
 "md": "https://dedupedai.com/use-cases/google-deepmind-alphafold3/choose-an-alphafold-3-weights-variant/index.md",
 "disclaimer": "Deduped lists open-source repositories that belong to other people. We do not own, maintain, audit, or vouch for any of them, and a repo appearing here is not an endorsement or a safety check. The use cases, steps, and prompts are written by AI and may be incomplete, outdated, or just wrong. Where a use case is marked \"Seen in the wild\", we link to public posts where someone described something similar, but we have not verified those posts and the use case itself is still our AI's own write-up. Use all of this at your own risk. Only run code, commands, or agents on systems and accounts you are authorized to use, and read the code and every command before you run it, especially anything that touches credentials, files, or the network. Nothing here is professional, security, legal, or financial advice. All trademarks and project names belong to their respective owners, and their use here does not imply affiliation. Content is provided as is, without warranties of any kind. Found a mistake, a safety problem, or something you want removed? Email hello@dedupedai.com and we will look at it promptly.",
 "api": "https://dedupedai.com/api/v1/usecases/google-deepmind-alphafold3--choose-an-alphafold-3-weights-variant.json",
 "api_version": "v1"
}