{
 "schema_version": 1,
 "generated": "2026-10-31",
 "repo": "google-deepmind/alphafold3",
 "name": "alphafold3",
 "owner": "google-deepmind",
 "slug": "google-deepmind-alphafold3",
 "github": "https://github.com/google-deepmind/alphafold3",
 "what": "AlphaFold 3 is Google DeepMind's inference pipeline for predicting the structure of biomolecular complexes. You describe the complex in a JSON input file and run run_alphafold.py, usually inside the provided container, with separate flags for the CPU heavy data pipeline and the GPU inference step. Model parameters are not in the repo: you must request them from Google and follow their terms of use.",
 "why": "8.7k stars, picked up by one AI source we track",
 "language": "",
 "requirements": [
  "The model parameters, which you may only use if received directly from Google, under the weights terms of use",
  "Docker and an NVIDIA GPU for the inference step",
  "The genetic and template databases for the data pipeline, mounted into the container",
  "A fold_input.json describing your sequences, model seeds, dialect and version"
 ],
 "audience_note": "Structural biology groups with GPU access who want to run AlphaFold 3 predictions themselves.",
 "risk": "none",
 "section": "earlier",
 "weekly_rank": null,
 "category": "Security and science",
 "url": "https://dedupedai.com/use-cases/google-deepmind-alphafold3/",
 "use_case_count": 3,
 "use_cases": [
  {
   "id": "google-deepmind-alphafold3--predict-a-complex-structure-with-alphafold-3",
   "title": "Predict a biomolecular complex from a JSON input",
   "best": true,
   "url": "https://dedupedai.com/use-cases/google-deepmind-alphafold3/predict-a-complex-structure-with-alphafold-3/",
   "json": "https://dedupedai.com/use-cases/u/google-deepmind-alphafold3/predict-a-complex-structure-with-alphafold-3.json"
  },
  {
   "id": "google-deepmind-alphafold3--split-the-alphafold-3-data-pipeline-from-inference",
   "title": "Run the CPU search and the GPU fold on different machines",
   "best": false,
   "url": "https://dedupedai.com/use-cases/google-deepmind-alphafold3/split-the-alphafold-3-data-pipeline-from-inference/",
   "json": "https://dedupedai.com/use-cases/u/google-deepmind-alphafold3/split-the-alphafold-3-data-pipeline-from-inference.json"
  },
  {
   "id": "google-deepmind-alphafold3--choose-an-alphafold-3-weights-variant",
   "title": "Pick the right AlphaFold 3 weights for your project",
   "best": false,
   "url": "https://dedupedai.com/use-cases/google-deepmind-alphafold3/choose-an-alphafold-3-weights-variant/",
   "json": "https://dedupedai.com/use-cases/u/google-deepmind-alphafold3/choose-an-alphafold-3-weights-variant.json"
  }
 ],
 "disclaimer": "Third-party repos we don't own or vouch for. AI-generated use cases can be wrong: review everything and run at your own risk."
}